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CASE REPORT
Tuberculous cervical lymphadenitis after BCG immunotherapy for bladder cancer A case report and review of the literature
1
Respiratory Failure Unit, Aristotle University of Thessaloniki
2
Pulmonary Department, Medical School,
Aristotle University of Thessaloniki
3
Internal Medicine Department,
G. Papanikolaou Hospital, Thessaloniki, Greece
4
Radiology Department,
G. Papanikolaou Hospital, Thessaloniki, Greece
Corresponding author
Serafeim-Chrysovalantis Kotoulas
Serafeim-Chrysovalantis Kotoulas, Resident of Respiratory Medicine, Respiratory Failure Unit, "G. Papanikolaou" General Hospital, Thessaloniki, Greece, 105 Agiou Stefanou street, 57010 Pylaia – Chortiatis, Thessaloniki, Greece
Serafeim-Chrysovalantis Kotoulas, Resident of Respiratory Medicine, Respiratory Failure Unit, "G. Papanikolaou" General Hospital, Thessaloniki, Greece, 105 Agiou Stefanou street, 57010 Pylaia – Chortiatis, Thessaloniki, Greece
Pneumon 2020;33(3):143-147
KEYWORDS
bacille calmette-guerin bladder cancer immunotherapy cervical lymphadenitis abscess lemierre’s syndrome
ABSTRACT
Since its introduction in 1976, Bacille Calmette-Guerin (BCG) has become the standard of care in high risk non-muscle-invasive bladder cancer. Apart from its efficacy, BCG immunotherapy is also considered to be safe. However, in addition to its common adverse effects, which are mild, it can rarely cause serious adverse effects, which can be life threatening.In this report, the case of an 85-year old male, who developed tuberculous cervical lymphadenitis and abscess after BCG immunotherapy is described.The patient presented with acute renal failure. During his hospitalization he also developed hepatitis because of the anti-tuberculous therapy and eventually passed away, probably by septic emboli originated from his right jugular vein which was infiltrated by his abscess.Tuberculous cervical lymphadenitis accompanied with abscess is a quite rare complication of BCG immunotherapy, but clinicians should be aware of it, as it can be proved fatal.
ABBREVIATIONS
BCG: Bacillus Calmette-Guérin, CT: computed tomography
ACKNOWLEDGEMENTS
This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.
CONFLICTS OF INTEREST
None
FUNDING
This research did not receive any specific grant from funding agencies in the public, commercial, or not-forprofit sectors.
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| eISSN: | 1791-4914 |
| ISSN: | 1105-848X |
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