ORIGINAL PAPER
The role of diabetes mellitus and obesity in COVID 19 patients
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1
Internist – Intensivist, Consultant, Department of Emergency Medicine, University Hospital “Attikon”, Athens, Greece
2
Professor Critical Care Medicine, Department of Critical Care Medicine, University Hospital “Attikon”, Athens, Greece
3
Assist. Professor Internal Medicine, 2nd Propaedeutic Department of Internal Medicine, University Hospital “Attikon” Athens, Greece
Corresponding author
Maria Panagiota Almyroudi
Department of Emergency Medicine,
“Attikon” University Hospital, School of Medicine,
National and Kapodistrian University of Athens,
1 Rimini Street, 12462, Haidari, Greece
Pneumon 2020;33(3):114-117
KEYWORDS
ABSTRACT
Several risk factors (old age, hypertension, cardiovascular disease, immunodeficiency) have been related with coronavirus disease 2019 (COVID 19). Among them, Diabetes Mellitus (DM) and obesity are recognized to increase the susceptibility and severity of the infection. A higher inflammatory response observed in these patients, the immune system dysfunction and increased expression of angiotensin converting enzyme 2 (ACE2) which is a the target for SARS-CoV-2, contribute to the worse outcome of diabetic and obese patients. Adequate blood glucose control improves the prognosis, while critically ill COVID 19 patients with high metabolic risk should be monitored for new onset DM.
CONFLICTS OF INTEREST
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