ORIGINAL STUDY
The health related quality of life of Greek patients with chronic obstructive pulmonary disease
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1
9th Department of Pulmonary Medicine, National and Kapodistrian University of Athens, Athens Chest Hospital “Sotiria”, Athens, Greece
2
3rd Department of Pulmonary Medicine, National
and Kapodistrian University of Athens, Athens
Chest Hospital “Sotiria”, Athens, Greece
3
1st Department of Pulmonary Medicine, National and Kapodistrian University of Athens, Athens Chest Hospital “Sotiria”, Athens, Greece
Corresponding author
Charalampos Dimitropoulos
9th Department of Pulmonary Medicine, Athens Chest
Hospital “Sotiria”, 152 Mesogion Ave., 11527 Athens,
Greece
Pneumon 2013;26(2):139-151
KEYWORDS
ABSTRACT
Background:
Chronic Obstructive Pulmonary Disease
(COPD) is an advancing disease, characterized by progressive deterioration of lung function. The impact of the disease on human
health is massive and it affects the health related quality of life
(HRQoL) of patients in every aspect. This study assessed HRQoL of
Greek patients with COPD and its association with demographic and
clinical factors, and compared the findings with with those of COPD
studies in other countries. In addition, the cost of pharmaceutical
treatment of these patients was assessed.
Material and Methods:
The study group consisted of 136 Greek patients with COPD (103
men, mean age 64.7±9.2 years, mean FEV1 59±25.6% predicted).I
Information was recorded about their demographic and clinical
parameters. Their HRQoL was assessed using the Greek versions of
the Medical Outcomes Study Short Form 12 (SF-12) and St George’s
Respiratory Questionnaire (SGRQ).
Results:
The HRQoL of Greek
patients with COPD was found to be significantly lower than both
that in the general population and that of patients COPD reported
in other countries. Almost all the HRQoL scores were shown to be
associated with gender, educational and financial status, duration
of symptoms, age at onset of symptoms, pack-years of cigarettes
smoked, disease stage, degree of dyspnoea, pO2 and pCO2 levels,
numbers of medical visits and hospital admissions, participation
in rehabilitation programmes, and co-morbidities, such as cardiovascular disease and diabetes mellitus (DM). The average cost of
pharmaceutical treatment was assessed at 110 ± 63 € / month and
was associated with the stage of the disease, the smoking habit,
the degree of dyspnoea, annual numbers of medical visits and
admissions and nebulizer usage.
Conclusions:
The HRQoL of Greek
patients with COPD is influenced by multiple parameters, which
should all be taken into consideration when their treatment is being
planned. Cost-effective studies should be made on populations of
Greek patients with COPD and more emphasis should be placed on
rehabilitation programmes in Greece.
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