Therapy with biologics is now the first choice of add on therapy in
the management of severe asthma. However, little is known about
the consequences of poor adherence to therapy on asthma control
and lung function. Here, we report a case of an asthmatic patient
with severe eosinophilic asthma whose asthma was ameliorated by
mepolizumab use and whose symptoms had worsened, and asthma
control was lost after skipping one single dose of the drug.
CONFLICTS OF INTEREST
None.
FUNDING
None.
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Haldar P, Brightling CE, Singapuri A, et al. Outcomes after cessation of mepolizumab therapy in severe eosinophilic asthma: a 12-month follow-up analysis. J Allergy Clin Immunol 2014; 133:921-3.
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