A case of pulmonary hyalinizing granuloma is presented. The patient was a 61-year-old Caucasian male who was found to have multiple bilateral pulmonary nodules at a routine chest x-ray. The patient was asymptomatic and the nodules were considered as metastatic disease of an abdominal lesion. Complete imaging and extensive laboratory tests excluded the presence of any malignancy. No definite diagnosis was established either by brushing cytology or percutaneous fine needle biopsy. A nodule of the right lung was removed by open lung biopsy. Histological diagnosis was pulmonary hyalinizing granuloma, consisting of hyalinized collagen fibers and bundles infiltrated with chronic inflammatory cells. The patient remains asymptomatic, with no specific therapy and the imaging findings are the same till today, 30 months after the diagnosis. Pneumon 2001, 14 (2): 156-160