CASE REPORT
Miliary nocardiosis: Fatal sepsis in an immunocompromised patient
 
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Department of Respiratory Failure, G. Papanikolaou General Hospital of Thessaloniki, Aristotle University of Thessaloniki, Thessaloniki, Greece
 
 
Submission date: 2021-04-21
 
 
Acceptance date: 2021-04-21
 
 
Publication date: 2021-06-18
 
 
Corresponding author
Evangelia Panagiotidou   

24 N. Plastira Str, 54250, Thessaloniki, Greece
 
 
Pneumon 2020;33(4):1-4
 
KEYWORDS
ABSTRACT
We present a rare case of pulmonary nocardiosis presenting as rapidly progressive sepsis with a miliary radiologic pattern in an immunocompromised patient, with a history of idiopathic membranous nephritis under treatment with cyclosporine and methylprednisolone. Pulmonary nocardiosis presents high mortality and nonspecific clinical and radiological features. The most usual radiological patterns are alveolar opacities, consolidation, nodules, masses, reticulonodular opacities, and pleural effusion. On the other hand, a miliary pattern can occur in tuberculosis, fungal infection, viral pneumonia, malignancy, sarcoidosis, tropical pulmonary eosinophilia, hypersensivity pneumonitis, silicosis and other rare conditions. Clinical suspicion is important as microbiological isolation requires 2-7 days. Awareness around nocardiosis needs to be raised as its frequency increases in parallel with the increase of cytotoxic and steroid treatment. Pneumon 2020, 33(4):1-4.
CONFLICTS OF INTEREST
None.
DATA AVAILABILITY
The data supporting this research cannot be made available for privacy or other reasons.
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