CASE REPORT
Miliary nocardiosis: Fatal sepsis in an immunocompromised patient
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Department of Respiratory Failure, G. Papanikolaou General Hospital of Thessaloniki, Aristotle University
of Thessaloniki, Thessaloniki, Greece
Submission date: 2021-04-21
Acceptance date: 2021-04-21
Publication date: 2021-06-18
Pneumon 2020;33(4):1-4
KEYWORDS
ABSTRACT
We present a rare case of pulmonary nocardiosis presenting as
rapidly progressive sepsis with a miliary radiologic pattern in an immunocompromised
patient, with a history of idiopathic membranous
nephritis under treatment with cyclosporine and methylprednisolone.
Pulmonary nocardiosis presents high mortality and nonspecific clinical
and radiological features. The most usual radiological patterns are
alveolar opacities, consolidation, nodules, masses, reticulonodular
opacities, and pleural effusion. On the other hand, a miliary pattern
can occur in tuberculosis, fungal infection, viral pneumonia, malignancy,
sarcoidosis, tropical pulmonary eosinophilia, hypersensivity
pneumonitis, silicosis and other rare conditions. Clinical suspicion is
important as microbiological isolation requires 2-7 days. Awareness
around nocardiosis needs to be raised as its frequency increases in
parallel with the increase of cytotoxic and steroid treatment.
Pneumon 2020, 33(4):1-4.
CONFLICTS OF INTEREST
None.
DATA AVAILABILITY
The data supporting this research cannot be made available for privacy or other reasons.
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