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REVIEW
Is Vitamin C supplementation beneficial in asthmatic patients?
1
Pneumonology Department, “G. Papanikolaou” General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece
Corresponding author
Konstantinos Porpodis
Pulmonary University Clinic, Aristotle University of Thessaloniki, “G. Papanikolaou” General Hospital, Thessaloniki, Greece
Pulmonary University Clinic, Aristotle University of Thessaloniki, “G. Papanikolaou” General Hospital, Thessaloniki, Greece
Pneumon 2017;30(3):151-156
ABSTRACT
As asthma prevails worldwide, nutritional hypotheses appear to suggestthat vitamin C supplementation may have a positive effect inasthma management. However, scientific community has not reachedan agreement concerning the association between vitamin C andasthma. In this review, we provide evidence of several in vitro andin vivo studies in mouse, rat and pig models that implicate vitaminC in immune response and also as an anti-inflammatory agent withantiviral properties. Finally, whether vitamin C supplementation inasthmatics is beneficial or not, a number of systematic reviews andmeta-analyses have tried to shed more light in this controversy,but no robust assessment concerning the use of vitamin C in themanagement of asthma is available.
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