COVID-19 associated Aspergillosis

Maria Panagiota Almyroudi; George Dimopoulos

2/2020 vol. 33

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SHORT REVIEW

COVID-19 associated Aspergillosis

Maria Panagiota Almyroudi ¹

George Dimopoulos ²

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Internist – Intensivist, Consultant, Department of Emergency Medicine, University Hospital ATTIKON, Athens, Greece

Professor Critical Care Medicine Department of Critical Care Medicine, University Hospital ATTIKON, Athens, Greece

Corresponding author

Maria Panagiota Almyroudi

Department of Emergency Medicine, “Attikon” University Hospital, School of Medicine, National and Kapodistrian University of Athens, 1 Rimini Street, 12462, Haidari, Greece

Pneumon 2020;33(2):1-4

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References (11)

KEYWORDS

Covid-19 associated pulmonary aspergillosis

invasive pulmonary aspergillosis

galactomannan

ABSTRACT

Invasive pulmonary aspergillosis (IPA) may complicate severe COVID-19 patients. The incidence, although is not well confirmed, varies (20-35%) and the already recognized host factors for IPA in immunosuppressed patients are not identified in non-immunocompromised patients with COVID-19 associated pulmonary aspergillosis (CAPA). Additionally, clinical characteristics and radiological findings are not specific. Given the probable high burden of the co-infection, a screening diagnostic work-up, including serum and BAL galactomannan measurement, fungal cultures of upper and lower respiratory tract samples are considered mandatory in all mechanically ventilated patients with COVID-19.

ABBREVIATIONS

IPA: Invasive pulmonary aspergillosis, CAPA: COVID-19 associated pulmonary aspergillosis, BAL: bronchoalveolar lavage

CONFLICTS OF INTEREST

None

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