BRIEF REVIEW
Beyond apnoea
 
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1
Neurologist, Adjunct Lecturer Neurology Department, Aiginitio Hospital, University of Athens, Sleep Study Centre, Evangelismos Hospital, Sleep Study Centre, St. Thomas’s Hospital, Guy’s and St. Thomas’s NHS Foundation Trust, London
 
2
Associate Professor, Sleep Study Centre, Evangelismos Hospital, University of Athens
 
 
Pneumon 2009;22(1):94-102
 
KEYWORDS
ABSTRACT
Chronic sleep deprivation, resulting from either socio-occupational habits or disorders compromising sleep, is considered to be a major cause of social, occupational and personal dysfunction, but it is also one of the most common contributing factors to mortality and physical disability. With the exception of obstructive apnoea, which accounts for the greater part of all diagnostic and therapeutic procedures related to sleep disorders, the majority of disorders remain undetected and untreated. The coexistence of more than one sleep disorder in the same patient is not uncommon, especially in certain groups of patients, such as those with neuromuscular and neurodegenerative diseases. In these cases, partial diagnosis is equivalent to no diagnosis. The aim of this review is to present the most common sleep disorders, other than obstructive apnoea, which independently or in combination are responsible for the majority of complaints concerning chronic sleep deprivation.
 
REFERENCES (36)
1.
Sigurdson K, Ayas NT. The public health and safety consequences of sleep disorders. Can J Physiol Pharmacol. 2007 Jan;85(1):179-83.
 
2.
Mitler MM, Carskadon MA, Czeisler CA, Dement WC, Dinges DF, Graeber RC. Catastrophes, sleep, and public policy: consensus report. Sleep.1988;11(1):100-9.
 
3.
Banks S, Dinges DF. Behavioral and physiological consequences of sleep restriction. J Clin Sleep Med. 2007 Aug 15;3(5):519-28.
 
4.
Eckert DJ, Jordan AS, Merchia P, Malhotra A. Central sleep apnea: Pathophysiology and treatment. Chest. 2007;131(2):595- 607.
 
5.
Javaheri S. Sleep disorders in systolic heart failure: a prospective study of 100 male patients. The final report. Int J Cardiol. 2006 Jan 4;106(1):21-8.
 
6.
Obermeyer WH, Benca RM. Effects of drugs on sleep. Neurol Clin. 1996 Nov;14 (4):827-40.
 
7.
Teichtahl H, Wang D. Sleep-disordered breathing with chronic opioid use. Expert Opin Drug Saf. 2007;6(6):641-9.
 
8.
Robbins J, Redline S, Ervin A, Walsleben JA, Ding J, Nieto FJ. Associations of sleep-disordered breathing and cerebral changes on MRI. J Clin Sleep Med. 2005 Apr 15;1(2):159-65.
 
9.
Chen ML, Keens TG. Congenital central hypoventilation syndrome: not just another rare disorder. Paediatr Respir Rev. 2004;5(3):182-9.
 
10.
Sanders MH, Givelber R. Sleep disordered breathing may not be an independent risk factor for diabetes, but diabetes may contribute to the occurrence of periodic breathing in sleep. Sleep Med. 2003;4(4):349-50.
 
11.
Resnick HE, Redline S, Shahar E, Gilpin A, Newman A, Walter R, Ewy GA, Howard BV, Punjabi NM; Sleep Heart Health Study. Diabetes and sleep disturbances: findings from the Sleep Heart Health Study. Diabetes Care. 2003;26(3):702-9.
 
12.
Thomson S, Morrell MJ, Cordingley JJ, Semple SJ. Ventilation is unstable during drowsiness before sleep onset. J Appl Physiol. 2005 Nov;99(5):2036-44.
 
13.
Bonakis A, Howard R, Williams A. a severely sleep deprived man. J Clin Sleep Med [Epub ahead of print].
 
14.
Xie A, Wong B, Phillipson EA, et al. Interaction of hyperventilation and arousal in the pathogenesis of idiopathic central sleep apnea. Am J Respir Crit Care Med 1994;150:489–495.
 
15.
D. Pevernagie, J. P. Janssens, W. De Backer, M. Elliott, J. Pepperell, and S. Andreas Ventilatory support and pharmacological treatment of patients with central apnoea or hypoventilation during sleep. Eur. Respir. Rev., Dec 2007; 16: 115 – 124.
 
16.
Banno K, Okamura K, Kryger MH. Adaptive servo-ventilation in patients with idiopathic Cheyne-Stokes breathing. J Clin Sleep Med. 2006 Apr 15;2(2):181-6.
 
17.
Baier PC, Trenkwalder C. Circadian variation in restless legs syndrome. Sleep Med. 2007 Sep;8(6):645-50.
 
18.
Patrick LR. Restless legs syndrome: pathophysiology and the role of iron and folate. Altern Med Rev. 2007 Jun;12(2):101- 12.
 
19.
Winkelmann J, Ferini-Strambi L. Genetics of restless legs syndrome. Sleep Med Rev. 2006 Jun;10(3):179-83.
 
20.
Konofal E, Cortese S, Marchand M, Mouren MC, Arnulf I, Lecendreux M. Impact of restless legs syndrome and iron deficiency on attention-deficit/hyperactivity disorder in children. Sleep Med. 2007 Nov;8(7-8):693-4.
 
21.
Hornyak M, Feige B, Voderholzer U, Philipsen A, Riemann D. Polysomnography findings in patients with restless legs syndrome and in healthy controls: a comparative observational study. Sleep. 2007 Jul 1;30(7):861-5.
 
22.
Allen RP. Improving RLS diagnosis and severity assessment: polysomnography, actigraphy and RLS-sleep log. Sleep Med. 2007 Aug;8 Suppl 2:S13-8.
 
23.
M.M. Ohayon and T. Roth, Prevalence of restless legs syndrome and periodic limb movement disease in the general population. J Psychosom Res 53 (2002), pp. 547–554.
 
24.
Hornyak M, Feige B, Riemann D, Voderholzer U. Periodic leg movements in sleep and periodic limb movement disorder: prevalence, clinical significance and treatment.Sleep Med Rev. 2006 Jun;10(3):169-77.
 
25.
Baran AS, Richert AC, Douglass AB, May W, Ansarin K. Change in periodic limb movement index during treatment of obstructive sleep apnea with continuous positive airway pressure. Sleep. 2003 Sep;26(6):717-20.
 
26.
Schenck CH, Boyd JL, Mahowald MW. A parasomnia overlap disorder involving sleepwalking, sleep terrors, and REM sleep behavior disorder in 33 polysomnographically confirmed cases. Sleep. 1997 Nov;20(11):972-81.
 
27.
Remulla A, Guilleminault C. Somnambulism (sleepwalking). Expert Opin Pharmacother. 2004 Oct;5(10):2069-74.
 
28.
Boeve BF, Silber MH, Saper CB, Ferman TJ, Dickson DW, Parisi JE, Benarroch EE, Ahlskog JE, Smith GE, Caselli RC, Tippman-Peikert M, Olson EJ, Lin SC, Young T, Wszolek Z, Schenck CH, Mahowald MW, Castillo PR, Del Tredici K, Braak H. Pathophysiology of REM sleep behavior disorder and relevance to neurodegenerative disease.Brain. 2007 Nov;130(Pt 11):2770-88.
 
29.
Iranzo A, Santamarνa J. Severe obstructive sleep apnea/hypopnea mimicking REM sleep behavior disorder. Sleep. 2005 Feb 1;28(2):203-6.
 
30.
Bonakis Α, Howard SR, Ebrahim OI, Merritt S, Williams JA. REM Sleep Behavior Disorder (RBD) and Its Associations in Young Patients. Sleep Medicine (2008) [Epub ahead of print].
 
31.
Gugger JJ, Wagner ML. Rapid eye movement sleep behavior disorder. Ann Pharmacother. 2007 Nov;41(11):1833-41.
 
32.
Knudsen S, Mikkelsen JD, Jennum P. Antibodies in narcolepsy-cataplexy patient serum bind to rat hypocretin neurons. Neuroreport. 2007 Jan 8;18(1):77-9.
 
33.
American Academy of Sleep Medicine. International classification of sleep disorders, 2nd ed.: diagnostic and coding manual. Westchester, Illinois: American Academy of Sleep Medicine; 2005.
 
34.
Martνnez-Rodrνguez JE, Iranzo A, Casamitjana R, Graus F, Santamaria J. Comparative analysis of patients with narcolepsy-cataplexy, narcolepsy without cataplexy and idiopathic hypersomnia. Med Clin (Barc). 2007 Mar 17;128(10):361-4.
 
35.
Dominguez-Ortega L, Salin-Pascual RJ, Dνaz-Gαllego E. Narcolepsylike symptoms in a patient with down syndrome and without obstructive sleep apnea. Sleep. 2003 May 1;26(3):285-6.
 
36.
Chabas D, Foulon C, Gonzalez J, Nasr M, Lyon-Caen O, Willer JC, Derenne JP, Arnulf I. Eating disorder and metabolism in narcoleptic patients. Sleep. 2007 Oct 1;30(10):1267-73.
 
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