PNEUMON Online First

PNEUMON Online First manuscripts have recently been accepted for publication in the PNEUMON Quarterly Medical Journal. They are published here in their accepted form, prior to copyediting and typesetting. After these production processes are complete and the authors have approved the resulting proofs, articles move to the latest issue of the PNEUMON online.

Pneumon 2020, 33(4):1-4
Miliary nocardiosis: Fatal sepsis in an immunocompromised patient
Authors Information

Department of Respiratory Failure,
General Hospital of Thessaloniki
“G. Papanikolaou”, Aristotle University
of Thessaloniki, Thessaloniki, Greece


We present a rare case of pulmonary nocardiosis presenting as rapidly progressive sepsis with a miliary radiologic pattern in an immunocompromised patient, with a history of idiopathic membranous nephritis under treatment with cyclosporine and methylprednisolone. Pulmonary nocardiosis presents high mortality and nonspecific clinical and radiological features. The most usual radiological patterns are alveolar opacities, consolidation, nodules, masses, reticulonodular opacities, and pleural effusion. On the other hand, a miliary pattern can occur in tuberculosis, fungal infection, viral pneumonia, malignancy, sarcoidosis, tropical pulmonary eosinophilia, hypersensivity pneumonitis, silicosis and other rare conditions. Clinical suspicion is important as microbiological isolation requires 2-7 days. Awareness around nocardiosis needs to be raised as its frequency increases in parallel with the increase of cytotoxic and steroid treatment.

Pneumon 2020, 33(4):1-4.