October - December 2017:
Volume 30, Issue 4

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Pneumon 2017, 30(4):255-260
Coexistence of pulmonary arteriovenous malformation and inferior vena cava agenesis in a patient presenting with hemoptysis
Authors Information
1: Pulmonary Department, Aristotle University of Thessaloniki, G.H. “G. Papanikolaou”, Thessaloniki, Greece
2: Thoracic Surgery Department, G.H. “G. Papanikolaou”, Thessaloniki, Greece
3: Radiology Department, G.H. “G. Papanikolaou”, Thessaloniki, Greece

Introduction: Pulmonary arteriovenous malformations (PAVMs) are abnormal vascular connections, mostly associated with hereditary hemorrhagic teleangiectasia (HHT), an autosomal vascular disorder. Inferior vena cava (IVC) agenesis is a rare congenital abnormality, reported to be associated with idiopathic deep venous thrombosis and pulmonary embolism in young patients. A coexistence of pulmonary arteriovenous malformation with IVC agenesis has only been described once in published literature. Case presentation: We present the case of a 24-year-old, Greek male with a history of recurrent episodes of hemoptysis. Evaluation confirmed the coexistence of a pulmonary arteriovenous malformation with IVC agenesis. The patient underwent a right lower lobectomy and remains asymptomatic at follow-up. Conclusion: PAVMs are rare causes of hemoptysis. Given the very limited epidemiologic evidence of IVC agenesis, we could not theorize that this entity presents a true association. As unanswered questions remain regarding the pathogenetic correlation of these vascular malformations, further investigation is needed on PAVMs and their pathogenesis.