October - December 2017:
Volume 30, Issue 4

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Pneumon 2017, 30(4):243-254
The effects of obstructive sleep apnea syndrome (OSAS) on the executive functions of the brain before and after treatment
Authors Information
1: Department of Respiratory Medicine, Sleep-related Breathing Disorders Laboratory, University of Thessaly Medical School Larissa, Greece
2: Sleep Study Unit, Eginition Hospital, University of Athens Medical School, Athens, Greece
Purpose: To summarize the information of published studies on the effect of OSAS on the executive functions of the brain in adult patients before and after any treatment. Method: An extensive literature search was performed on the Pub Med database. Results: The OSAS inarguably causes neurocognitive deficit and reduced activation of brain regions responsible for cognitive function. The methods of treatment are: by a continuous positive air pressure (CPAP) device, mandibular treatment and tonsillectomy. These methods of treatment offer some protection to the cognitive areas of the brain. The severity of the syndrome correlates significantly with the scores of various neuropsychological batteries; these batteries vary even if they evaluate the same function. Conclusions: The severity of the syndrome is responsible for the degree of neurocognitive dysfunction. The most prevalent form of treatment is the use of a device with positive air pressure CPAP which acts as a protective factor in neurocognitive functions. Further research is needed because few studies have evaluated the effects of treatment using a CPAP device while the timeframe and the population that needs to be studied remain uncertain.