July - September 2017:
Volume 30, Issue 3

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Pneumon 2017, 30(3):151-156
Is Vitamin C supplementation beneficial in asthmatic patients?
Authors Information
Pneumonology Department, “G. Papanikolaou” General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece

As asthma prevails worldwide, nutritional hypotheses appear to suggestthat vitamin C supplementation may have a positive effect inasthma management. However, scientific community has not reachedan agreement concerning the association between vitamin C andasthma. In this review, we provide evidence of several in vitro andin vivo studies in mouse, rat and pig models that implicate vitaminC in immune response and also as an anti-inflammatory agent withantiviral properties. Finally, whether vitamin C supplementation inasthmatics is beneficial or not, a number of systematic reviews andmeta-analyses have tried to shed more light in this controversy,but no robust assessment concerning the use of vitamin C in themanagement of asthma is available.