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July - September 2017:
Volume 30, Issue 3

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Pneumon 2017, 30(3):141-150
Outcome of tuberculosis treatment at the pulmonary - tuberculosis department of A.U.TH. during the three-year period 2012-2014
Authors Information
Pulmonary-Tuberculosis Department, Aristotle University of Thessaloniki, “G. Papanikolaou” Hospital, Exohi, Thessaloniki, Greece
Abstract

INTRODUCTION: Tuberculosis remains a serious threat to public health and one of the leading causes of death among infectious diseases. Monitoring treatment outcome is necessary in order to assess the effectiveness of the therapeutic intervention and to identify possible obstacles to disease control. In that setting outcome is an important indicator of the effectiveness of TB control programs. MATERIAL AND METHODS: This is a retrospective study of TB patients registered at the Department of Pulmonary Medicine Aristotle University of Thessaloniki (AUTH), in the period from January 1st, 2012 to December 31st, 2014. RESULTS: 89 patients aged 49.5±19.20 years were recorded. 67.5 % were men. 68.5% of patients were of Greek origin and 91% suffered from pulmonary TB. In 78.7% of patients the diagnosis was confirmed microbiologically. 11.2% presented with monoresistance or polydrug resistance to anti-TB drugs. The positive outcome rate of the TB treatment was 67.5%, of which 38.2% were cured and 29.3% completed the treatment. The outc ome was negative in 32.5% of patients and rates that corresponded specifically to death, treatment failure, loss to follow-up and lack of evaluation were 4.5%, 1.1%, 2.2% and 24.7% respectively. CONCLUSION: The positive outcome rate of TB among patients was lower than the WHO global target of 85%. There is a clear need for a comprehensive management of problems in TB monitoring in Greece, both in terms of its impact and its outcome.